Advanced MRI Morphologic Study Shows No Atrophy in Healthy Individuals with Hippocampal Hyperintensity
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CLINICAL REPORT BRAIN AdvancedMRIMorphologic Study Shows No Atrophy in Healthy Individuals with Hippocampal Hyperintensity
SUMMARY: Wehave already shown that brainMR imaging of healthy individuals frequently reveals either unilateral or bilateral Hh, which is considered a hallmark of hippocampal sclerosis.We performed a follow-up (5-year interval) clinical and advanced imaging study of these individuals to address whether Hhmay havemasked occult brain atrophy or contributed to a later onset of epilepsy. Subjects wi...
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BACKGROUND New-onset Alzheimer disease (AD) is often attributed to degenerative changes in the hippocampus. However, the contribution of regionally distributed small vessel cerebrovascular disease, visualized as white matter hyperintensities (WMHs) on magnetic resonance imaging, remains unclear. OBJECTIVE To determine whether regional WMHs and hippocampal volume predict incident AD in an epidem...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2013
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a3458